I read a great post recently by Anthony Tjan entitled Entrepreneurial DNA: Do You Have It? on the Harvard Business blog.
In the article, Mr. Tjan argues that entrepreneurs have a distinct profile that is obvious to those familiar with it. He says,
"Entrepreneurs hold an idealism and risk profile that makes them fundamentally different. They don't think about security--in fact they are often uncomfortable with it. And they have the guts to bet it over and over again. They think less about what they lack and more about what they can achieve with what they have. In a sea of ambiguity, they forge ahead with an incredible fortitude."
It's an interesting read and good food for thought for any physician considering entrepreneurship as a career.